OR4C3

Across TCGA patient cohorts, OR4C3 mutation is significantly associated with the RNA expression of many other genes, with 435 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR4C3-associated genes across cancer lineages are RN7SL330P, MIR507, and RNA5SP235. Each is linked with OR4C3 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4C3-to-partner and partner-to-OR4C3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL330P grouped by OR4C3-low versus OR4C3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C3→partner) and Y-score (partner→OR4C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL330P →	+0.088	+1.766	<.001	.003	3	3
PRAD	MIR507 →	+0.363	+7.939	<.001	.008	3	2
HNSC	RNA5SP235 →	+0.233	+6.038	<.001	<.001	3	2
HNSC	MIR558 →	+0.336	+3.813	<.001	.007	3	2
CESC	TRGV11 →	+0.086	+3.996	.002	.005	3	2
CESC	DNAJA1P1 →	+0.039	+4.891	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 435 associations by consensus.

RN7SL330P by OR4C3 expression — SKCM

Explore this box plot interactively →