OR4C3

Across TCGA cell cohorts, OR4C3 RNA expression is significantly associated with the mutation status of many other genes, with 20 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR4C3-associated genes across cancer lineages are USPL1, PPP1R3A, and TCF3. Each is linked with OR4C3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C3-to-partner and partner-to-OR4C3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USPL1 grouped by OR4C3-low versus OR4C3-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C3→partner) and Y-score (partner→OR4C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	USPL1 →	+4.984	+0.012	.002	<.001	3	1
BLOOD_Leukemia	PPP1R3A →	+3.569	+0.006	.009	<.001	3	1
BLOOD_Leukemia	TCF3 →	+3.569	+0.006	.009	<.001	3	1
BREAST	NUP155 →	+3.781	+0.028	.009	<.001	3	1
BREAST	GPR158 →	+4.196	+0.034	.006	<.001	3	1
BREAST	GPRIN2 →	+4.781	+0.042	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

USPL1 by OR4C3 expression — BLOOD_Leukemia

Explore this box plot interactively →