OR4C16

Across TCGA patient cohorts, OR4C16 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible OR4C16-associated genes across cancer lineages are CSH1, LALBA, and OR10H5. Each is linked with OR4C16 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C16-to-partner and partner-to-OR4C16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSH1 grouped by OR4C16-low versus OR4C16-high in SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C16→partner) and Y-score (partner→OR4C16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	CSH1 →	+0.312	+5.189	<.001	.006	3	1
SCLC	LALBA →	+0.260	+4.847	<.001	.009	3	1
SCLC	OR10H5 →	+0.127	+5.624	<.001	.003	3	1
SCLC	SPANXC →	+0.303	+5.189	<.001	.006	3	1
SCLC	GRXCR2 →	+0.133	+4.847	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CSH1 by OR4C16 expression — SCLC

Explore this box plot interactively →