OR4C16

Across TCGA cell cohorts, OR4C16 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR4C16-associated genes across cancer lineages are ODAM, RBMY1E, and CHP2. Each is linked with OR4C16 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C16-to-partner and partner-to-OR4C16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ODAM grouped by OR4C16-low versus OR4C16-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C16→partner) and Y-score (partner→OR4C16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	ODAM →	+0.100	+3.220	.004	.002	3	2
LUNG_NSCLC_LUSC	RBMY1E →	+0.820	+4.643	.002	.008	3	1
LUNG_SCLC	CHP2 →	+0.146	+3.209	.009	.005	3	1
LUNG_SCLC	CYP4Z1 →	+0.176	+4.013	.002	<.001	3	1
LUNG_SCLC	GPR33 →	+0.021	+2.874	<.001	.007	3	1
SKIN	TTC29 →	+0.480	+3.872	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ODAM by OR4C16 expression — LUNG_SCLC

Explore this box plot interactively →