OR4C15

Across TCGA patient cohorts, OR4C15 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4C15-associated genes across cancer lineages are TFRC, Acetyl-a-Tubulin-Lys40, and CD31. Each is linked with OR4C15 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR4C15-to-partner and partner-to-OR4C15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by OR4C15-low versus OR4C15-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C15→partner) and Y-score (partner→OR4C15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TFRC →	+0.698	+2.700	<.001	.005	3	3
SKCM	Acetyl-a-Tubulin-Lys40 →	+0.472	+2.115	.006	<.001	3	3
UCEC	CD31 →	-0.182	-2.115	.004	.019	3	3
STAD	PDCD4 →	-0.429	-3.169	.049	.019	3	2
LUAD	FoxM1 →	+0.197	+1.887	.041	.029	3	2
LUAD	ACC1 →	+0.387	+1.584	.008	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

TFRC by OR4C15 expression — LUAD

Explore this box plot interactively →