OR4C15

Across TCGA cell cohorts, OR4C15 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR4C15-associated genes across cancer lineages are CLPSL1, EDDM3B, and SMIM23. Each is linked with OR4C15 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4C15-to-partner and partner-to-OR4C15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLPSL1 grouped by OR4C15-low versus OR4C15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4C15→partner) and Y-score (partner→OR4C15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CLPSL1 →	+0.140	+4.376	<.001	<.001	3	2
URINARY_TRACT	EDDM3B →	+0.066	+5.087	<.001	.004	3	1
URINARY_TRACT	SMIM23 →	+0.013	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUSC	TMEM235 →	+0.007	+4.584	<.001	.001	3	1
OVARY	GUCY2F →	+0.006	+4.263	.006	.002	3	1
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

CLPSL1 by OR4C15 expression — LARGE_INTESTINE

Explore this box plot interactively →