OR4B1

Across TCGA pan-cancer cohorts, OR4B1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated OR4B1 data layer compared with 10 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher OR4B1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR4B1 expression acts as an unfavorable survival marker.

STAD, BLCA, and SKCM are the cancer types where OR4B1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	II,III,IV	0.149	0.690	<.001	18	view →
BLCA	OS	Median	IV	0.153	0.599	.018	9	view →
SKCM	DFS	Median	IV	0.134	0.589	.031	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

OR4B1–STAD (DFS)

Open the STAD breakdown →