OR4B1

Across TCGA cell cohorts, OR4B1 RNA expression is significantly associated with the mutation status of many other genes, with 23 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR4B1-associated genes across cancer lineages are EXD2, MYBL2, and CDK6. Each is linked with OR4B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4B1-to-partner and partner-to-OR4B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EXD2 grouped by OR4B1-low versus OR4B1-high in LUNG_SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4B1→partner) and Y-score (partner→OR4B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	EXD2 →	+5.029	+0.062	.006	<.001	3	1
LUNG_SCLC	MYBL2 →	+5.029	+0.055	.006	<.001	3	1
LUNG_SCLC	CDK6 →	+5.029	+0.044	.006	<.001	3	1
LUNG_SCLC	KLC1 →	+5.029	+0.062	.006	<.001	3	1
LUNG_SCLC	ENAM →	+5.029	+0.044	.006	<.001	3	1
LUNG_SCLC	TPTE2 →	+5.029	+0.044	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

EXD2 by OR4B1 expression — LUNG_SCLC

Explore this box plot interactively →