OR4A47

Across TCGA patient cohorts, OR4A47 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4A47-associated genes across cancer lineages are eIF4G, ER-alpha_pS118, and N-Ras. Each is linked with OR4A47 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4A47-to-partner and partner-to-OR4A47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4G grouped by OR4A47-low versus OR4A47-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4A47→partner) and Y-score (partner→OR4A47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	eIF4G →	+0.571	+3.000	.035	.036	3	2
STAD	ER-alpha_pS118 →	+0.088	+3.000	.045	.036	3	1
STAD	N-Ras →	-0.125	-3.000	.040	.036	3	1
STAD	Paxillin →	+0.472	+3.000	.045	.036	3	1
STAD	RBM15 →	+0.657	+3.000	.004	.033	3	1
SKCM	YB-1 →	+0.150	+1.597	.039	.040	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

eIF4G by OR4A47 expression — STAD

Explore this box plot interactively →