OR4A46P

Across TCGA pan-cancer cohorts, OR4A46P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated OR4A46P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher OR4A46P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR4A46P expression acts as an unfavorable survival marker.

LIHC, ESCA, and BRCA are the cancer types where OR4A46P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	II,III,IV	0.201	0.719	.002	54	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	51	view →
BRCA	OS	Tertile	IV	0.233	0.755	.038	48	view →
UVM	OS	Tertile	All	0.220	0.917	<.001	36	view →
SKCM	DFS	Tertile	All	0.037	0.762	<.001	36	view →
KIRP	DFS	Tertile	All	0.709	0.865	.019	21	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
CHOL	OS	Tertile	All	0.089	0.673	.018	18	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	18	view →
PCPG	OS	Tertile	All	0.539	0.848	.012	18	view →
KICH	DFS	Tertile	All	0.521	0.906	.042	12	view →
SARC	OS	Tertile	All	0.478	0.749	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

OR4A46P–LIHC (OS)

Open the LIHC breakdown →