OR4A16

Across TCGA patient cohorts, OR4A16 mutation is significantly associated with the RNA expression of many other genes, with 3,342 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4A16-associated genes across cancer lineages are SUPV3L1, BNIP3, and RPS29P1. Each is linked with OR4A16 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR4A16-to-partner and partner-to-OR4A16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUPV3L1 grouped by OR4A16-low versus OR4A16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4A16→partner) and Y-score (partner→OR4A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SUPV3L1 →	+0.372	+2.818	.002	<.001	3	4
UCEC	BNIP3 →	+0.728	+3.343	.002	.005	3	4
STAD	RPS29P1 →	+0.668	+4.254	<.001	.008	3	4
COAD	S100A11P6 →	+0.708	+3.661	<.001	.002	3	3
UCEC	DLAT →	+0.618	+1.925	<.001	.005	3	3
UCEC	PAXIP1 →	+0.431	+2.346	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,342 associations by consensus.

SUPV3L1 by OR4A16 expression — UCEC

Explore this box plot interactively →