OR4A16

Across TCGA cell cohorts, OR4A16 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR4A16-associated genes across cancer lineages are OR9Q1, USP17L8, and OR14C36. Each is linked with OR4A16 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4A16-to-partner and partner-to-OR4A16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9Q1 grouped by OR4A16-low versus OR4A16-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4A16→partner) and Y-score (partner→OR4A16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR9Q1 →	+0.006	+5.754	<.001	.002	3	1
BLOOD_Leukemia	USP17L8 →	+0.003	+4.384	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR14C36 →	+0.008	+3.944	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR52A1 →	+0.024	+3.665	<.001	<.001	3	1
LUNG_NSCLC_LUAD	SLC35G4 →	+0.012	+3.944	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR52E1 →	+0.020	+3.944	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

OR9Q1 by OR4A16 expression — CNS

Explore this box plot interactively →