OR4A15

Across TCGA cell cohorts, OR4A15 mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR4A15-associated genes across cancer lineages are TEX55, CPXCR1, and PSG6. Each is linked with OR4A15 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4A15-to-partner and partner-to-OR4A15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX55 grouped by OR4A15-low versus OR4A15-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4A15→partner) and Y-score (partner→OR4A15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TEX55 →	+0.066	+3.273	<.001	<.001	3	2
LUNG_SCLC	CPXCR1 →	+0.026	+3.070	.002	.009	3	2
LUNG_SCLC	PSG6 →	+0.046	+3.938	.001	<.001	3	2
LUNG_SCLC	OR5B21 →	+0.051	+3.684	<.001	.001	3	2
LUNG_NSCLC_LUAD	GRK7 →	+0.064	+3.865	<.001	<.001	3	2
PANCREAS	C7orf77 →	+0.046	+5.614	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

TEX55 by OR4A15 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →