OR3A3

Across TCGA patient cohorts, OR3A3 mutation is significantly associated with the RNA expression of many other genes, with 2,398 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR3A3-associated genes across cancer lineages are RN7SL47P, ZCCHC14, and OR51A7. Each is linked with OR3A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR3A3-to-partner and partner-to-OR3A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL47P grouped by OR3A3-low versus OR3A3-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR3A3→partner) and Y-score (partner→OR3A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL47P →	+0.143	+3.996	<.001	.005	3	2
UCEC	ZCCHC14 →	+0.483	+2.332	.003	.003	3	2
LUAD	OR51A7 →	+0.042	+4.444	<.001	.006	3	2
LUAD	RPSAP25 →	+0.065	+3.336	.007	.008	3	2
COAD	MTCO3P16 →	+0.148	+4.893	<.001	.005	3	2
UCEC	MED28P1 →	+0.206	+2.531	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,398 associations by consensus.

RN7SL47P by OR3A3 expression — CESC

Explore this box plot interactively →