OR3A3

RNA expression — cross-omics
Cross-omicsRNA → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR3A3 RNA expression is significantly associated with the drug of many other genes, with 85 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible OR3A3-associated genes across cancer lineages are Selisistat, Temsirolimus, and AZD7969. Each is linked with OR3A3 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR3A3-to-partner and partner-to-OR3A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Selisistat grouped by OR3A3-low versus OR3A3-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR3A3→partner) and Y-score (partner→OR3A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCSelisistat →+0.272+0.026.007.00633
LUNG_NSCLC_LUADTemsirolimus →-0.390-0.011.023.01433
OVARYAZD7969 →-0.577-0.030.013.02933
OVARYDactolisib →-0.576-0.063.006.03533
OVARY5-Fluorouracil →-0.959-0.030.005.02933
OVARY965-D2 →-0.383-0.030.016.04233
Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

Selisistat by OR3A3 expression — LUNG_NSCLC_LUSC

Box plot of Selisistat in OR3A3-low vs OR3A3-high samples in LUNG_NSCLC_LUSC.

Explore this box plot interactively →

Exploration