OR2Z1

Across TCGA cell cohorts, OR2Z1 RNA expression is significantly associated with the mutation status of many other genes, with 70 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR2Z1-associated genes across cancer lineages are MTMR3, EXPH5, and RRBP1. Each is linked with OR2Z1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2Z1-to-partner and partner-to-OR2Z1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTMR3 grouped by OR2Z1-low versus OR2Z1-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2Z1→partner) and Y-score (partner→OR2Z1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MTMR3 →	+3.977	+0.033	.007	<.001	3	1
SOFT_TISSUE	EXPH5 →	+4.977	+0.050	.002	<.001	3	1
SOFT_TISSUE	RRBP1 →	+4.977	+0.050	.002	<.001	3	1
LUNG_NSCLC_LUSC	MORC2 →	+4.643	+0.030	.008	<.001	3	1
LUNG_NSCLC_LUSC	TOP3A →	+4.643	+0.030	.008	<.001	3	1
LUNG_NSCLC_LUSC	PLXNB2 →	+4.643	+0.030	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 70 associations by consensus.

MTMR3 by OR2Z1 expression — SOFT_TISSUE

Explore this box plot interactively →