OR2Z1

Across TCGA cell cohorts, OR2Z1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OR2Z1-associated genes across cancer lineages are NOBOX, CYLC2, and FAM240B. Each is linked with OR2Z1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2Z1-to-partner and partner-to-OR2Z1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOBOX grouped by OR2Z1-low versus OR2Z1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2Z1→partner) and Y-score (partner→OR2Z1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	NOBOX →	+0.025	+5.321	<.001	.005	3	1
CNS	CYLC2 →	+0.016	+5.321	<.001	.005	3	1
CNS	FAM240B →	+0.098	+4.981	<.001	.008	3	1
CNS	OOSP4A →	+0.074	+5.321	<.001	.005	3	1
LARGE_INTESTINE	CFHR2 →	+0.038	+4.022	<.001	.006	3	1
SKIN	PLSCR5 →	+0.027	+4.095	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

NOBOX by OR2Z1 expression — CNS

Explore this box plot interactively →