OR2W5

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2W5 mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2W5-associated genes across cancer lineages are JNK2, Stathmin, and 14-3-3_beta. Each is linked with OR2W5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2W5-to-partner and partner-to-OR2W5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2W5→partner) and Y-score (partner→OR2W5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCJNK2 →+0.346+3.169<.001.01732
LUSCStathmin →-0.128-1.990.040.03132
SKCM14-3-3_beta →-0.117-2.700.043.00632
SKCMFOXO3a →-0.106-2.000.040.03132
SKCMMre11 →-0.132-3.559.043.00232
SKCM4E-BP1_pS65 →+0.236+2.334.007.01832
Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

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