Across TCGA pan-cancer cohorts, OR2W1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OR2W1 data layer compared with 11 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher OR2W1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR2W1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

ESCA, LIHC, and UCS are the cancer types where OR2W1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Median	II,III,IV	0.080	0.523	<.001	18	view →
LIHC	OS	Median	II,III,IV	0.093	0.716	<.001	18	view →
UCS	DFS	Median	All	0.126	0.523	.009	6	view →
UCEC	DFS	Median	II,III,IV	1.000	0.444	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: OR2W1 tumor-vs-normal RNA expression · all OR2W1 data types