Across TCGA patient cohorts, OR2V2 mutation is significantly associated with the RNA expression of many other genes, with 4,176 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2V2-associated genes across cancer lineages are RNU6-607P, RPL34P23, and MRPL49P2. Each is linked with OR2V2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2V2-to-partner and partner-to-OR2V2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2V2→partner) and Y-score (partner→OR2V2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-607P →	+0.267	+3.360	<.001	.006	3	3
SARC	RPL34P23 →	+0.219	+4.995	<.001	.002	3	3
CESC	MRPL49P2 →	+0.076	+6.342	<.001	.001	3	2
UCEC	ATP1B3P1 →	+0.288	+3.392	<.001	.006	3	2
UCEC	KMT2B →	+0.374	+3.480	.006	.002	3	2
UCEC	RAE1 →	+0.422	+4.343	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,176 associations by consensus.

Exploration

OR2V2 survival (RNA) · tumor vs normal (RNA) · all OR2V2 data types