Across TCGA cell cohorts, OR2V2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2V2-associated genes across cancer lineages are MSMB, TMCO5A, and H2BC1. Each is linked with OR2V2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2V2-to-partner and partner-to-OR2V2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2V2→partner) and Y-score (partner→OR2V2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MSMB →	+0.341	+3.774	<.001	.008	3	1
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	H2BC1 →	+0.462	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	GPR171 →	+0.040	+4.093	<.001	.004	3	1
LUNG_NSCLC_LUAD	DAOA →	+0.014	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	KRTAP10-5 →	+0.011	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

OR2V2 survival (RNA) · tumor vs normal (RNA) · all OR2V2 data types