OR2U2P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR2U2P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated OR2U2P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher OR2U2P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR2U2P expression acts as an unfavorable survival marker, although some lineages such as OV and LUSC show a favorable association.

KIRC, BLCA, and UCS are the cancer types where OR2U2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSTertileAll0.4480.662<.001129view →
BLCADFSTertileIII,IV0.3200.577.01436view →
UCSDFSTertileIV0.1320.718.00236view →
ESCADFSTertileII,III,IV0.1250.838.00627view →
SKCMOSTertileIII,IV0.3150.708.00327view →
OVOSTertileIII,IV0.8280.667.00424view →
CHOLDFSTertileAll0.0370.486.00118view →
LUSCDFSTertileAll1.0000.739.03012view →
LGGOSTertileAll0.2310.453.0249view →
LIHCDFSTertileII,III,IV0.0800.414.0279view →
SARCOSTertileAll0.6800.862.0356view →
Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

OR2U2P–KIRC (OS)

Kaplan–Meier survival curve for OR2U2P RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration