OR2T34

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR2T34 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OR2T34 data layer compared with 12 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher OR2T34 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR2T34 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LUAD, SKCM, and SCLC are the cancer types where OR2T34 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSMedianIII,IV0.1710.669.00112view →
SKCMDFSMedianII,III,IV0.3410.303.0148view →
SCLCOSMedianII,III,IV0.1520.777.0383view →
LUSCDFSMedianII,III,IV0.1390.663.0273view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OR2T34–LUAD (OS)

Kaplan–Meier survival curve for OR2T34 mutant vs wild-type samples in LUAD.

Open the LUAD breakdown →

Exploration