OR2T34

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR2T34 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2T34-associated genes across cancer lineages are KRTAP13-2, ARMH2, and OR12D3. Each is linked with OR2T34 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T34-to-partner and partner-to-OR2T34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP13-2 grouped by OR2T34-low versus OR2T34-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T34→partner) and Y-score (partner→OR2T34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCKRTAP13-2 →+0.229+4.643<.001.00831
LUNG_NSCLC_LUSCARMH2 →+0.020+4.643<.001.00831
LUNG_NSCLC_LUADOR12D3 →+0.035+5.228<.001.00531
LUNG_NSCLC_LUADNLRP8 →+0.054+4.887<.001.00931
LUNG_NSCLC_LUADBPY2 →+0.006+5.228<.001.00531
LUNG_NSCLC_LUADBPY2B →+0.006+5.228<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

KRTAP13-2 by OR2T34 expression — LUNG_NSCLC_LUSC

Box plot of KRTAP13-2 in OR2T34-low vs OR2T34-high samples in LUNG_NSCLC_LUSC.

Explore this box plot interactively →

Exploration