OR2T3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2T3 mutation is significantly associated with the RNA expression of many other genes, with 762 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2T3-associated genes across cancer lineages are SNORD111B, RPL12P3, and MIR6827. Each is linked with OR2T3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T3-to-partner and partner-to-OR2T3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T3→partner) and Y-score (partner→OR2T3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSNORD111B →+0.648+4.969<.001.00932
LGGRPL12P3 →+0.124+5.529<.001.00432
BLCAMIR6827 →+0.758+5.497<.001.00432
LUADRBMS3 →-0.754-3.432.001.00532
LUADCBR4 →-0.385-2.617.007.00632
LUADH2AB3 →+0.023+5.230<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 762 associations by consensus.

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