Across TCGA patient cohorts, OR2T3 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OR2T3-associated genes across cancer lineages are ERK2, Ku80, and PEA-15. Each is linked with OR2T3 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2T3-to-partner and partner-to-OR2T3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T3→partner) and Y-score (partner→OR2T3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ERK2 →	+0.384	+2.820	.018	.035	3	1
LUAD	Ku80 →	+0.287	+3.355	.014	.005	2	2
LUAD	PEA-15 →	-0.250	-3.000	.016	.035	3	1
LUAD	B-Raf →	+0.467	+2.186	.009	.034	3	1
LUAD	Caspase-7-cleavedD198 →	+0.459	+2.186	.039	.034	3	1
UCEC	EGFR_pY1173 →	+0.120	+2.196	.004	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

OR2T3 survival (RNA) · tumor vs normal (RNA) · all OR2T3 data types