Across TCGA cell cohorts, OR2T3 mutation is significantly associated with the mutation status of many other genes, with 289 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR2T3-associated genes across cancer lineages are ZNF512B, OR11G2, and ARHGDIG. Each is linked with OR2T3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T3-to-partner and partner-to-OR2T3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T3→partner) and Y-score (partner→OR2T3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ZNF512B →	+4.000	+4.000	.002	.002	1	2
CNS	OR11G2 →	+5.000	+4.044	.008	.008	1	2
CNS	ARHGDIG →	+5.000	+4.044	.008	.008	1	2
SKIN	EGLN2 →	+5.824	+5.824	.002	.002	1	2
CNS	OR8S1 →	+5.000	+4.044	.008	.008	1	2
LUNG_SCLC	DCAF8L1 →	+4.369	+3.066	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 289 associations by consensus.

Exploration

OR2T3 survival (RNA) · tumor vs normal (RNA) · all OR2T3 data types