Across TCGA patient cohorts, OR2T27 mutation is significantly associated with the RNA expression of many other genes, with 632 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2T27-associated genes across cancer lineages are VTRNA2-2P, ZFP91-CNTF, and MIR5688. Each is linked with OR2T27 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T27-to-partner and partner-to-OR2T27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T27→partner) and Y-score (partner→OR2T27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	VTRNA2-2P →	+0.315	+2.783	<.001	.007	3	2
SKCM	ZFP91-CNTF →	+0.078	+3.470	.002	.006	3	2
CESC	MIR5688 →	+0.669	+5.201	<.001	.007	3	2
SKCM	MIR4510 →	+0.217	+4.485	<.001	.004	3	2
UCEC	CIDECP1 →	+0.456	+3.513	<.001	.002	3	2
UCEC	IGHD6-6 →	+1.297	+3.935	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 632 associations by consensus.

Exploration

OR2T27 survival (RNA) · tumor vs normal (RNA) · all OR2T27 data types