Across TCGA cell cohorts, OR2T27 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR2T27-associated genes across cancer lineages are OR2T1, SLC35G4, and FASLG. Each is linked with OR2T27 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T27-to-partner and partner-to-OR2T27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T27→partner) and Y-score (partner→OR2T27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR2T1 →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	SLC35G4 →	+0.020	+4.906	<.001	.006	3	1
LUNG_SCLC	FASLG →	+0.099	+4.044	<.001	.009	3	1
LARGE_INTESTINE	DAZ4 →	+0.326	+4.977	<.001	.007	3	1
LARGE_INTESTINE	DAZ2 →	+0.336	+5.415	<.001	.004	3	1
LARGE_INTESTINE	RBMY1J →	+0.013	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

OR2T27 survival (RNA) · tumor vs normal (RNA) · all OR2T27 data types