OR2T11

Across TCGA cell cohorts, OR2T11 RNA expression is significantly associated with the mutation status of many other genes, with 44 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR2T11-associated genes across cancer lineages are HLA-DQB2, TMOD3, and ATG2A. Each is linked with OR2T11 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T11-to-partner and partner-to-OR2T11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HLA-DQB2 grouped by OR2T11-low versus OR2T11-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T11→partner) and Y-score (partner→OR2T11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HLA-DQB2 →	+3.269	+0.048	.007	.001	3	2
LARGE_INTESTINE	TMOD3 →	+4.415	+0.017	.007	<.001	3	2
LUNG_NSCLC_LUSC	ATG2A →	+4.643	+0.056	.008	<.001	3	1
LUNG_NSCLC_LUSC	MORC2 →	+4.643	+0.056	.008	<.001	3	1
LUNG_NSCLC_LUSC	TOP3A →	+4.643	+0.056	.008	<.001	3	1
LUNG_NSCLC_LUSC	PLXNB2 →	+4.643	+0.056	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

HLA-DQB2 by OR2T11 expression — BLOOD_Leukemia

Explore this box plot interactively →