OR2T1

Across TCGA cell cohorts, OR2T1 RNA expression is significantly associated with the mutation status of many other genes, with 74 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR2T1-associated genes across cancer lineages are THADA, BRPF3, and KHNYN. Each is linked with OR2T1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2T1-to-partner and partner-to-OR2T1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, THADA grouped by OR2T1-low versus OR2T1-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2T1→partner) and Y-score (partner→OR2T1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	THADA →	+3.316	+0.015	.003	<.001	3	2
OESOPHAGUS	BRPF3 →	+4.906	+0.013	.006	<.001	3	1
OESOPHAGUS	KHNYN →	+4.906	+0.013	.006	<.001	3	1
OESOPHAGUS	USP42 →	+4.906	+0.013	.006	<.001	3	1
OESOPHAGUS	TRPM6 →	+4.906	+0.013	.006	<.001	3	1
OESOPHAGUS	SAP130 →	+4.906	+0.013	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

THADA by OR2T1 expression — BLOOD_Leukemia

Explore this box plot interactively →