OR2M7

Across TCGA patient cohorts, OR2M7 mutation is significantly associated with the RNA expression of many other genes, with 2,056 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2M7-associated genes across cancer lineages are ELOA, GMNN, and PPP1R8. Each is linked with OR2M7 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2M7-to-partner and partner-to-OR2M7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOA grouped by OR2M7-low versus OR2M7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M7→partner) and Y-score (partner→OR2M7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ELOA →	+0.396	+1.818	.001	.002	3	3
UCEC	GMNN →	+0.511	+2.158	.007	<.001	3	3
UCEC	PPP1R8 →	+0.328	+2.032	.009	.005	3	3
UCEC	ADH5 →	+0.529	+2.955	<.001	<.001	3	3
UCEC	FDX1P2 →	+0.093	+2.287	.003	.001	3	3
SKCM	UBXN2A →	+0.537	+3.468	.008	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,056 associations by consensus.

ELOA by OR2M7 expression — UCEC

Explore this box plot interactively →