OR2M7

Across TCGA patient cohorts, OR2M7 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2M7-associated genes across cancer lineages are RBM15, ATM, and FASN. Each is linked with OR2M7 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2M7-to-partner and partner-to-OR2M7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBM15 grouped by OR2M7-low versus OR2M7-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M7→partner) and Y-score (partner→OR2M7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RBM15 →	+0.426	+3.016	.019	.019	3	2
UCEC	ATM →	-0.373	-3.156	.032	.018	3	2
LUAD	FASN →	+0.701	+3.000	.004	.036	2	2
UCEC	14-3-3_beta →	-0.083	-1.847	.030	.049	3	1
UCEC	EGFR_pY1068 →	-0.197	-1.678	.041	.023	3	1
UCEC	eIF4E →	+0.162	+2.087	.045	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

RBM15 by OR2M7 expression — LUAD

Explore this box plot interactively →