OR2M7

Across TCGA cell cohorts, OR2M7 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR2M7-associated genes across cancer lineages are GALP, USP17L17, and LGALS2. Each is linked with OR2M7 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2M7-to-partner and partner-to-OR2M7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALP grouped by OR2M7-low versus OR2M7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M7→partner) and Y-score (partner→OR2M7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GALP →	+0.017	+4.415	<.001	.007	3	1
SKIN	USP17L17 →	+0.010	+5.022	<.001	.002	3	1
LUNG_SCLC	LGALS2 →	+0.370	+4.269	<.001	.005	3	1
LUNG_SCLC	F9 →	+0.027	+4.643	<.001	.004	3	1
LUNG_SCLC	RNASE3 →	+0.077	+4.817	<.001	.001	3	1
LUNG_SCLC	LCE5A →	+0.626	+4.269	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

GALP by OR2M7 expression — SKIN

Explore this box plot interactively →