OR2M3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2M3 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2M3-associated genes across cancer lineages are PDCD4, PKC-a, and PKC-b-II_pS660. Each is linked with OR2M3 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR2M3-to-partner and partner-to-OR2M3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M3→partner) and Y-score (partner→OR2M3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPDCD4 →-0.463-2.459.004.01834
LUADPKC-a →-0.270-2.459.009.01832
LUADPKC-b-II_pS660 →-0.319-1.700.045.04332
LUADASNS →+0.380+3.169.044.01832
UCECCyclin-B1 →+0.513+1.440.008.02432
LUSCAcetyl-a-Tubulin-Lys40 →-0.551-1.691.021.04332
Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration