OR2M3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR2M3 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR2M3-associated genes across cancer lineages are IQCF6, CD300H, and H2BW2. Each is linked with OR2M3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2M3-to-partner and partner-to-OR2M3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M3→partner) and Y-score (partner→OR2M3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEIQCF6 →+0.311+4.467<.001.00431
LARGE_INTESTINECD300H →+0.033+4.415<.001.00731
SKINH2BW2 →+0.092+4.467<.001.00431
SKINBTN1A1 →+0.216+4.095<.001.00931
SKINRIT2 →+0.030+5.022<.001.00231
SKINOR1L3 →+0.022+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

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