Across TCGA patient cohorts, OR2M2 mutation is significantly associated with the RNA expression of many other genes, with 3,705 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2M2-associated genes across cancer lineages are C12orf43, RRAD, and RNF34. Each is linked with OR2M2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2M2-to-partner and partner-to-OR2M2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M2→partner) and Y-score (partner→OR2M2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C12orf43 →	+0.265	+2.839	.005	.001	3	3
UCEC	RRAD →	-1.393	-2.247	.001	.002	3	3
UCEC	RNF34 →	+0.306	+2.095	.008	.003	3	3
UCEC	LSM1 →	+0.500	+2.743	.002	.002	3	3
UCEC	UFD1 →	+0.456	+2.790	<.001	<.001	3	3
UCEC	NUFIP1 →	+0.600	+2.269	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,705 associations by consensus.

Exploration

OR2M2 survival (RNA) · tumor vs normal (RNA) · all OR2M2 data types