Across TCGA patient cohorts, OR2M2 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2M2-associated genes across cancer lineages are MEK1, ASNS, and BRD4. Each is linked with OR2M2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2M2-to-partner and partner-to-OR2M2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M2→partner) and Y-score (partner→OR2M2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.454	+3.807	.001	<.001	3	2
UCEC	ASNS →	+0.407	+1.584	.004	.036	3	2
UCEC	BRD4 →	+0.229	+2.321	.029	.033	3	2
UCEC	53BP1 →	+0.298	+1.584	.026	.036	3	2
UCEC	Di-Ras3 →	-0.141	-2.308	.015	.033	3	2
LUSC	Rab25 →	+0.332	+2.816	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

OR2M2 survival (RNA) · tumor vs normal (RNA) · all OR2M2 data types