Across TCGA cell cohorts, OR2M2 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR2M2-associated genes across cancer lineages are CLEC4D, UBE2QL1, and NEXMIF. Each is linked with OR2M2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2M2-to-partner and partner-to-OR2M2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M2→partner) and Y-score (partner→OR2M2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CLEC4D →	+0.006	+4.643	<.001	.008	3	1
LARGE_INTESTINE	UBE2QL1 →	+0.214	+3.722	<.001	.007	3	1
LARGE_INTESTINE	NEXMIF →	+0.212	+2.933	<.001	.003	3	1
SKIN	SPINK9 →	+0.043	+4.415	<.001	.007	3	1
CNS	DSG4 →	+0.027	+4.169	<.001	.008	3	1
CNS	FCAR →	+0.059	+4.472	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

OR2M2 survival (RNA) · tumor vs normal (RNA) · all OR2M2 data types