OR2M1P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR2M1P Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OR2M1P data layer compared with 11 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher OR2M1P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR2M1P expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

HNSC, LGG, and UCEC are the cancer types where OR2M1P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSMedianAll0.1560.710.00224view →
LGGOSMedianAll0.1820.909<.00112view →
UCECOSMedianIV0.2310.592.0366view →
SKCMOSMedianII,III,IV1.0000.725.0373view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OR2M1P–HNSC (OS)

Kaplan–Meier survival curve for OR2M1P mutant vs wild-type samples in HNSC.

Open the HNSC breakdown →

Exploration