OR2M1P

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2M1P mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2M1P-associated genes across cancer lineages are ARID1A, VHL, and ATM. Each is linked with OR2M1P in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2M1P-to-partner and partner-to-OR2M1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARID1A grouped by OR2M1P-low versus OR2M1P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2M1P→partner) and Y-score (partner→OR2M1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECARID1A →-0.221-2.989.027.03531
UCECVHL →-1.276-3.000<.001.03631
UCECATM →-0.612-3.000.009.03631
UCECCaspase-7-cleavedD198 →+0.770+2.827.013.03531
UCEC14-3-3_beta →-0.151-3.308.004.01021
UCECShc_pY317 →-0.221-3.000.005.03621
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

ARID1A by OR2M1P expression — UCEC

Box plot of ARID1A in OR2M1P-low vs OR2M1P-high samples in UCEC.

Explore this box plot interactively →

Exploration