Across TCGA patient cohorts, OR2L3 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2L3-associated genes across cancer lineages are p27_pT198, NDRG1_pT346, and Caspase-7-cleavedD198. Each is linked with OR2L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2L3-to-partner and partner-to-OR2L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2L3→partner) and Y-score (partner→OR2L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT198 →	+0.120	+2.115	.010	.019	3	2
LUAD	NDRG1_pT346 →	+0.745	+3.321	.006	.010	3	1
LUSC	Caspase-7-cleavedD198 →	+0.753	+3.009	.003	.019	2	2
UCEC	INPP4B →	-0.305	-3.321	.030	.009	3	1
UCEC	STAT3_pY705 →	-0.390	-2.311	<.001	.034	3	1
UCEC	VHL →	-0.888	-2.584	.002	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

OR2L3 survival (RNA) · tumor vs normal (RNA) · all OR2L3 data types