Across TCGA cell cohorts, OR2L3 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2L3-associated genes across cancer lineages are OR2B11, C12orf40, and ACTL9. Each is linked with OR2L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2L3-to-partner and partner-to-OR2L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2L3→partner) and Y-score (partner→OR2L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR2B11 →	+0.048	+3.399	.004	.001	3	1
LUNG_SCLC	C12orf40 →	+0.021	+3.058	<.001	.004	3	1
LUNG_SCLC	ACTL9 →	+0.344	+3.169	.008	.005	3	1
LUNG_SCLC	TMPRSS11B →	+0.041	+3.392	.002	.001	3	1
LUNG_SCLC	SPANXN5 →	+0.058	+3.099	<.001	.003	3	1
LUNG_SCLC	OR51A2 →	+0.086	+2.874	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

OR2L3 survival (RNA) · tumor vs normal (RNA) · all OR2L3 data types