OR2J2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2J2 mutation is significantly associated with the RNA expression of many other genes, with 1,162 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2J2-associated genes across cancer lineages are MRPL51P2, SLC29A4P1, and RNU2-35P. Each is linked with OR2J2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2J2-to-partner and partner-to-OR2J2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2J2→partner) and Y-score (partner→OR2J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCMRPL51P2 →+0.138+7.169<.001<.00132
CESCSLC29A4P1 →+0.036+4.384<.001.00832
SKCMRNU2-35P →+0.150+1.818.002.00232
CESCHAUS1P3 →+0.035+4.757<.001.00432
LUADLCN1P2 →+0.260+5.213<.001<.00132
LUADOR2W4P →+0.026+4.418.005.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,162 associations by consensus.

Exploration