Across TCGA pan-cancer cohorts, OR2H1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated OR2H1 data layer compared with 17 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher OR2H1 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated OR2H1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, CHOL, and SKCM are the cancer types where OR2H1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.937	0.435	.014	18	view →
CHOL	DFS	Median	All	0.045	0.486	.009	15	view →
SKCM	DFS	Median	IV	0.036	0.433	<.001	12	view →
LIHC	OS	Median	All	0.262	0.673	.045	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: OR2H1 tumor-vs-normal RNA expression · all OR2H1 data types