Across TCGA patient cohorts, OR2H1 mutation is significantly associated with the total protein of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2H1-associated genes across cancer lineages are 4E-BP1, GSK3-a-b, and CDK1. Each is linked with OR2H1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2H1-to-partner and partner-to-OR2H1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2H1→partner) and Y-score (partner→OR2H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.306	+3.936	<.001	<.001	3	3
SKCM	GSK3-a-b →	+0.178	+3.203	.010	.008	3	3
SKCM	CDK1 →	+0.215	+3.000	.005	.035	3	3
UCEC	EGFR_pY1068 →	-0.218	-1.584	.008	.034	3	2
UCEC	eIF4E →	+0.155	+3.472	.026	.002	3	2
UCEC	Ku80 →	+0.210	+1.405	.006	.012	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

Exploration

OR2H1 survival (RNA) · tumor vs normal (RNA) · all OR2H1 data types