OR2G3

Across TCGA cell cohorts, OR2G3 RNA expression is significantly associated with the go_rna of many other GO terms, with 446 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR2G3-associated GO terms across cancer lineages are Modulation of inhibitory postsynaptic potential, Regulation of postsynaptic membrane neurotransmitter receptor levels, and Postsynapse to nucleus signaling pathway. Each is linked with OR2G3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2G3-to-partner and partner-to-OR2G3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Modulation of inhibitory postsynaptic potential grouped by OR2G3-low versus OR2G3-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2G3→partner) and Y-score (partner→OR2G3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Modulation of inhibitory postsynaptic potential →	-0.966	-0.012	<.001	.002	3	1
BLOOD_Leukemia	Regulation of postsynaptic membrane neurotransmitter receptor levels →	+0.058	+0.019	<.001	.006	3	1
BLOOD_Leukemia	Postsynapse to nucleus signaling pathway →	+0.112	+0.011	<.001	.004	3	1
BLOOD_Leukemia	Dorsal/ventral pattern formation →	+0.047	+0.011	.002	.006	3	1
BLOOD_Leukemia	Response to iron ion →	+0.116	+0.013	<.001	.001	3	1
BLOOD_Leukemia	Response to lead ion →	+0.122	+0.014	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 446 associations by consensus.

Modulation of inhibitory postsynaptic potential by OR2G3 expression — BLOOD_Leukemia

Explore this box plot interactively →