Across TCGA patient cohorts, OR2F1 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2F1-associated genes across cancer lineages are Shc_pY317, p62 Lck ligand, and MYH11. Each is linked with OR2F1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2F1-to-partner and partner-to-OR2F1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2F1→partner) and Y-score (partner→OR2F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Shc_pY317 →	-0.205	-2.584	.003	.011	3	3
UCEC	p62 Lck ligand →	+0.351	+2.179	.020	.034	3	2
SKCM	MYH11 →	-0.592	-1.514	.043	.014	3	1
SKCM	PDK1 →	+0.115	+2.188	.001	<.001	3	1
SKCM	SF2 →	+0.110	+1.247	.018	.043	3	1
SKCM	Src →	-0.181	-1.983	.020	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

OR2F1 survival (RNA) · tumor vs normal (RNA) · all OR2F1 data types