Across TCGA patient cohorts, OR2C3 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2C3-associated genes across cancer lineages are TFRC, Cyclin-B1, and Smac. Each is linked with OR2C3 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2C3-to-partner and partner-to-OR2C3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2C3→partner) and Y-score (partner→OR2C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TFRC →	+0.533	+2.321	.014	.032	3	3
UCEC	Cyclin-B1 →	+0.570	+3.584	.003	.002	3	3
LUAD	Smac →	+0.257	+2.115	.042	.018	3	2
UCEC	eIF4E →	+0.209	+3.000	.004	<.001	3	2
UCEC	Caspase-8 →	-0.245	-2.070	.004	.001	3	2
UCEC	4E-BP1 →	+0.225	+2.584	.016	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

OR2C3 survival (RNA) · tumor vs normal (RNA) · all OR2C3 data types