Across TCGA cell cohorts, OR2C3 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR2C3-associated genes across cancer lineages are OR4X2, USP17L15, and ECRG4. Each is linked with OR2C3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2C3-to-partner and partner-to-OR2C3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2C3→partner) and Y-score (partner→OR2C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR4X2 →	+0.010	+2.777	<.001	.004	3	2
LUNG_NSCLC_LUSC	USP17L15 →	+0.006	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUAD	ECRG4 →	+0.051	+3.089	<.001	<.001	3	1
LUNG_NSCLC_LUAD	LIPN →	+0.022	+2.777	<.001	.004	3	1
LUNG_NSCLC_LUAD	LCE1F →	+0.057	+3.440	<.001	.001	3	1
LUNG_NSCLC_LUAD	ETV3L →	+0.016	+2.678	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

OR2C3 survival (RNA) · tumor vs normal (RNA) · all OR2C3 data types